gosh the way Sandrone contribution in Dottore fight and Columbina comeback is just peak cinema.

She using both Alain mathematics and Rene World-Formula in search of a possibility that Columbia comeback. Sandrone's magnum opus, Rene and Alain Chymical Marriage(lol). That is something Rene was always wished for when he was alive: two of them working together to save the world, but Alain was never took the end of the world talk seriously before it too late for them.(check Alain diary).

Personally, I think this is the peak of "power of friendship". Even if is doomed one, is because Rene and Alain once mutual friendship, Sandrone adapt both of their legacy abd create a miracle.

As for her as a character, there is just a lot to said. In Luna II and III, she criticism Alain and Rene sacrifice tendency. Yet is not hard to tell she idolize Alain and quoting Rene a lot. Eg: when we first meet in Nod-Kraid, she said: "They offer said mortals, shackled by flesh and blood, may fail to perceived the truth of this world" — something Rene used to teach in the Ordo, nearly word by word.

Sandrone's appearance is another top notch. Her mek body is modeled after Mary-Ann. Her personality is affected by Alain a lot: both of them are not good with express emotion, yet deeply care. Her dress however is another interesting story, the symbol of 4 cycles and moons is something taken after Rene and Jakob doomsday clocks. She always wears this dress even in her flashbacks so I think Alain made this.

(Lord Artificer is yearnatron 3000, confirmed.)
Sandrone and the peak cinema of so called Narzissenkreuz legacy